Clinical Studies
Clinical Studies
Informed decisions are better decisions. Biogetica supports you in your right to know and choose. We are here to give natures medicines and whole person healing the respect it deserves and hope you will join us in this pertinent quest today.
When it comes to your health, there can be no compromises.** Which is why, to inform you better on various conditions, we have put together a knowledge base of research white papers from the best of practitioners in the field of natural therapies. These include ground breaking precedent setting research on our meticulously crafted products and research on the ingredients in them as well. Our entire product design and ingredient selection process is evidence based and we carefully study each possible ingredient before designing a kit that includes the best of what nature has to offer.
All of this research has been published in Peer reviewed medical journals after a stringent review process. Some of it is also hosted by on Pubmed.gov the US National Library of Medicine. It is beautiful to see that practitioners from all medical traditions are now beginning to realise the importance of nature in health and wellness. Pharmaceuticals may manage symptoms but they do precious little to rejuvenate our bodies and their organ systems. This is where natural health products come in and there is now ample evidence to show that nature plays a critical part in our wellbeing!
Please note: Biogetica presents the research as it is, without making any claims about the methods discussed. If you want more information on a particular condition, you might consider talking to your Doctor or one of ours.

Conditions
Clinical Studies
Acne
- Several clinical studies have indicated that plant extracts may help maintain clear skin. Due to these properties, plant-based modalities are being extensively studied for acne especially since antibiotics and hormones usually applied to treat acne are often accompanied by severe side effects and drug resistance over a period of time.
- A clinical study showed that the extract of T.chebula (an ingredient in our kit) showed significant inhibition of the acne producing Propioni bacterium acnes strain.
- Nearly all the participants enrolled in an observational study to test a natural complex reported statistically significant improvement in the acne lesions. Thus, suggesting that the natural ingredient may potentially alleviate acne especially of the inflammatory kind.
ADHD
- 75% out of 115 ADHD patients responded to natural treatments, reaching a clinical improvement rating of 73% and only 22% of the patient group needed additional treatment of Methylphenidate, the conventional drug in the treatment of ADHD. Moreover, no side effects were reported, which is a major concern for patients on conventional medicine for ADHD.
- A clinical trial to test the efficacy of Bacopa monnieri (included in our kit) on ADHD children reported that the extract of B monnieri potentially alleviated the symptoms of ADHD and was well-tolerated by the children.
Alcoholism
- Heavy drinkers treated with a herb extract for 7 days showed significant reduction in alcohol consumption. The urge to drink also drastically reduced and no notable side effects were observed.
- Lab subjects treated with a natural complex caused significant reduction in alcohol intake after an oral treatment for 15 days. The results indicated that the natural tincture successfully induced increased aversion to alcohol on completion of the protocol.
Allergies
- In an international multicenter, prospective, observational study, 82.6% of patients suffering from allergies responded to Natural Treatment as compared to 68% that responded to conventional medicines. Also, 22.3 % on conventional medicine reported adverse events versus 7.8% in the natural remedies group. The number of very satisfied patients was also higher in the natural treatment group.
- A prospective multicenter observational study on allergic patients reported that the given natural complex substantially improved symptoms of all the enrolled patients. 62% were able to discontinue at least one conventional medication, while the remaining 38% reported a dose reduction in at least one medication. No side effects were reported either.
- Patients reported significant positive changes in their allergic –specific symptoms and improved quality of life after taking a natural preparation for 4 weeks in a double-blind clinical trial comparing the natural preparation and a placebo. Moreover, subjects taking the test ingredient reported no adverse event during the trial period.
Alopecia
- Independent clinical investigations have reported that herbs possess active constituents that potentially stimulate hair growth, increase tenacity and retard apoptosis of cells in the hair follicles.
- 86.9% of Alopecia areata patients reported hair re-growth after applying a juice of Allium cepa L (an ingredient in our kit) for 6 weeks and the result was significantly higher among males (93.7%) compared to females (71.4%).
Amenorrhea
- Several clinical studies have identified phytoestrogens in herbs that exhibit estrogenic and / or antiestrogenic effects, which potentially work to maintain a healthy menstrual cycle without the toxic side effects of conventional treatments like hormone replacement therapy (HRT). Researchers admit HRT increases the risk of cardiovascular diseases, stroke, osteoporosis, and even cancer.
- An In vitro examination to determine the effects of Daucus carota( an ingredient in our kit) on progesterone levels reported the extract causing a decrease in progesterone secretion. This decreasing effect on hormonal levels may benefit in normalizing alterations in menstrual function.
Anemia
- A clinical evaluation of Ayurvedic preparations in a randomized non-blinded trial on iron deficiency anemic patients showed a clinically significant increase in all the blood parameters after 30 days. Moreover, the Ayurvedic preparations were well tolerated as compared to Conventional treatment with iron salts, which is associated with various side effects like heartburn, nausea, upper gastric discomfort, constipation and diarrhoea in the patients.
- Of the 219 anemic adolescents included in the study protocol, the ones given individual Ferrum phos 3X doses (included in our kits) and its combination with constitutional natural remedies showed statistically significant increase in hemoglobin levels.
Anti-Aging
- A clinical study of a herbal extract showed 97% inhibition of collagenase activity and 64% inhibition of elastase activity, which indicates good efficacy of the extract as an anti-wrinkle agent. Moreover, the bioactive compounds present in the herbs were found to remove free radicals from skin cells, prevent trans-epidermal water loss, and also have a sun protection factor to protect the skin from wrinkles, leading to glowing and healthy younger skin. [1, 2]
- Clinical investigations on Withania somnifera indicated that the herbal extract exerted significant anti-aging effects in normal healthy but aged subjects. Reports also showed the extract influencing positive changes on mental functions and memory. The findings indicated that the free radical scavenging effects of withania played a role owing to its anti-stress, immunomodulatory, nootropic, anti-inflammatory and anti-aging effects.
Anxiety
- A group of adult participants with generalized anxiety disorders displayed a significant reduction in their clinical anxiety scores after enrolling for a one-month herb regimen in the double-blinded trial conducted.
- In a double-blind, placebo-controlled study, all patients scheduled for surgery reported significantly lesser anxiety scores on the anxiety clinical scale after being administered oral Passiflora (an ingredient in our CP 30 – FACTOR) before surgery. The findings indicate that Passiflora incarnata as a premedication may reduce anxiety without inducing sedation.
- Another In vivo study comparing Passiflora with Diazepam reported that although both of the test substances displayed anxiolytic behavior, Passiflora had no adverse effects on the memory parameters of the lab subjects, whereas diazepam disrupted their memory process.
Arthritis
- All the physical and biochemical changes observed in clinical subjects suffering from Arthritis were altered to near normal conditions after being put on an oral ayurvedic formulation. Moreover, the formulation also showed a potent inhibitory effect on the enzymes that contributed significantly to cartilage degradation.
- 87% of the osteoarthritic patients enrolled in an open, multicenter trial of a natural preparation were satisfied with the remedy and 76% stated they would use it again. In fact, almost all the patients of the trial reported significant reduction in pain, stiffness and functional disability after applying it topically for 6 weeks. Moreover, the formulation was reported safe and well tolerated with only 7.6% reporting side effects.
Asthma
- 70 % of asthmatic patients enrolled in a double-blinded trial reported significant improvement in all asthmatic complaints after being on an Ayurvedic formulation for 6 weeks. The results are promising, especially as conventional asthmatic treatments only suppress symptoms and cause an array of side effects in the body.
- 78% of the 1773 asthmatic patients given an ayurvedic formulation in a clinical study rated the efficacy as excellent, very good or good and 75% of the patients reported the tolerability of the formulation as excellent, very good or good.
Atherosclerosis
- Both In vitro and In vivo studies on a polyherbal formulation highlighted that the herbal blend potentially prevented atherosclerosis by inhibiting key inflammatory mediators and enzyme-mediated LDL oxidation.
- An In vivo study to determine the anti-atherogenic activity of Terminalia arjuna (an ingredient in our kit) on hypercholesterolemic subjects reported that the herb significantly decreased levels of bad cholesterol, increased HDL and lessened atherosclerotic lesions.
Athlete's Foot
- All the patients of the trial infected with the human pathogenic fungi causing Tinea pedis (Athlete’s foot), Tinea corporis or Tinea cruris, showed significant improvement in their condition after topically applying a broad spectrum herbal oil, and 60% of them reported being completely free from the infection. None of the patients in the study reported a relapse when re-examined.
- Several in vitro and in vivo clinical studies have reported that nitric acid (homeopathic nitric acidum) exhibits considerable antimicrobial activity against bacteria, yeast, fungi and viruses The antifungal activity of the preparation is attributed to its ability to inhibit microbial proliferation. So, clinical evidence collected has highlighted that a 20-min treatment with nitric oxide-releasing solution (NORS) may be sufficient to eradicate fungi associated with Athlete’s Foot.
Carpal Tunnel Syndrome (CTS)
Cataract
- Clinical studies have shown that alkaloids and polysaccharides available in herbs have an inhibitory effect on cataract caused by oxidative damage.
- An In vivo study demonstrated that an ethanolic extract of C. maritima exhibited free radical scavenging activities and could possibly help in maintaining normal vision.
Chlamydia infection
Chronic Fatigue
- Clinical research on lab subjects revealed that the test herb reversed stress parameters like despair behaviour, anxiety and decreased locomotor activity often seen in chronic fatigue syndrome (CFS). The results indicated that CFS may lead to oxidative stress that the plant extract mitigated owing to its antioxidant and anti-stress properties.
- Clinical subjects with chronic fatigue syndrome manifested as marked increase in immobility and heightened sensitivity to pain were put on an ayurvedic regimen to evaluate its therapeutic properties. The results suggested a marked decrease in the immobility and pain parameters indicating that the ayurvedic extract can serve as a valuable option in alleviating CFS.
Conjunctivitis
- 81.5% of conjunctivitis patients reported complete relief after administering Euphrasia rostkoviana Hayne (a constituent of our Eye 200 formula) eye drops for 14 days in the open label, multi-centered, multinational trial conducted. Moreover, none of the patients reported any serious adverse effects and the formulation was well tolerated.
- 93% of conjunctivitis patients reported more than 90% relief in symptoms while some of them indicated being totally symptom free, after they were given eye drops containing an ayurvedic formulation for 7 days in the clinical study conducted. Results also indicated that the test herb was devoid of any toxic effect and that it could safely substitute the modern management of infective conjunctivitis.
Cystitis
- Clinical analysis on Cyperus rotundus L. (an ingredient in our kits) revealed that the extract possesses versatile therapeutic properties. It was screened for its use in urinary tract infections like cystitis and was found to be a potent antiandrogenic, antibacterial, anti-inflammatory, antioxidant, and anti-uropathogenic agent. [1, 2]
Dementia
- Results from a double blind placebo controlled clinical trial confirmed the clinical efficacy of Ginkgo biloba in dementia of the Alzheimer type.
- Clinical studies on Bacopa monnieria extract showed significant improvement in mental control, logical memory and paired associated learning.
- Dementia patients put on a herb regimen for 4 weeks, in a randomized controlled trial, reported significant improvement in the behavioural and psychological symptoms of dementia and activities of daily living.
Edema
- Several Clinical studies have highlighted that Boerhaavia diffusa (an ingredient in our kit) possesses diuretic, anti-inflammatory, antifibrinolytic, anticonvulsant, antibacterial, anti-stress and hepato-protective properties. Due to the prevalence of diuretic and anti-inflammatory activities, this herb may benefit concerns such as edema.
- All of the 65 patients on a 6 week herb regimen clinical trial showed statistically significant improvement in their edema symptoms. The herbs were well tolerated with only 9% reporting mild adverse events.
Fibromyalgia
- Numerous clinical studies have indicated that the ayurvedic Boswellia herb (included in our kits) improves blood supply to the joints and repairs blocked blood vessels, thereby improving mobility. Boswellia has also shown to effectively shrink inflamed tissue, the underlying cause of pain in many conditions.
- All the patients that completed the test natural protocol showed significantly greater improvements in fibromyalgia symptoms, demonstrating that individualized natural remedies may successfully lessen associated pain and improve the quality of life and overall health of fibromyalgia patients.
Gingivitis
- Gingivitis patients included in a randomized controlled study, and given a natural remedy for 6 months, showed clinically significant reductions in the severity of gingivitis, dental plaques and bleeding tendencies. Moreover, the formulation also exhibited antimicrobial and antifungal activity. The remedy was well tolerated without any noticeable adverse effects like abscesses, ulcerations or allergic reactions.
- 76% of a group of Gingivitis patients with periodontal complaints such as gingival swelling and bleeding, bad breath, receding gingiva, and abscess benefitted after being administered natural remedies for 6 weeks. The results indicate that natural remedies can be invaluable in reducing dental pain and alleviating periodontal/dental problems.
Goiter
- Clinical subjects suffering from goiter showed higher levels of minerals and lesser damage to thyroid cells when administered iodine rich herbs as compared to those treated with synthetic iodine.
- The results are promising especially as other conventional hormone replacement therapies cause an array of side effects in the body.
Hair Loss
- In a study conducted, 0.03 % of Nano-Lipobelle DN CoQ10 (component of Anagrow) when applied to isolated hair follicles, enhanced follicular growth by 14% within 7 days.
- The hair growth initiation time on clinical subjects was significantly reduced to half on treatment with a 2% ethanol extract of a natural herb. They also exhibited greater number of hair follicles in the anagenic phase as compared to the minoxidil 2% solution used as positive control for comparison.
Herpes
- The Canadian Government recommends monolaurin to Herpes and HIV patients.
- Studies suggest that Potent Bio-energetic Imprints (such as 2L Herp) benefited 82% of Herpes cases.
- Independent studies conducted by the JSS college of pharmacy have shown that extracts of Hypericum mysorense demonstrated anti-viral activity in vitro.
- A recent study published in the peer reviewed “International Journal of Research in Ayurveda and Pharmacy” has shown that Hyperisince reduces: nerve pain, healing time of herpes outbreaks to one to three days, and the likelihood of future outbreaks. Over 76% of patients reported relief and over 80% of patients that took Hyperisince for 4 months or more never had another outbreak. These results are truly groundbreaking. A majority of patients rated Hyperisince 10 out of 10 and reported that the cold sore healing time and pain were lesser with Hyperisince than previously tried treatments such as Acyclovir.
HPV
Infertility
- A group of subfertile men given a natural remedy for 10.3 months, reported significant improvement in sperm density, percentage of sperm with good progressive motility, and density of sperm with good propulsive motility in the pilot study conducted.
- Comparative meta-analyses between traditional herbal extracts and western medicines revealed that management of female infertility with natural herbs could improve pregnancy rates 2-fold within a 3-6 month period as compared with Western medical fertility drug therapy. Moreover, the other fertility indicators were also positively influenced by herbal therapy; thus, indicating that herbs are effective in inducing a favourable environment for a viable pregnancy.
Insomnia
- Several clinical studies have highlighted that Valeriana officinalis possesses sleep inducing, anxiolytic, and tranquilizing properties. Moreover, the mild hypnotic effects of valerian have also shown to decrease sleep latency and improve sleep quality.
- A group of patients suffering from sleep onset insomnia, given Withania somnifera (included in our kits) reported a significant reduction in sleep latency and were able to fall asleep faster. Moreover, there were no side effects reported as compared to conventional hypnotics and sedatives that are notorious for the side effects they bring along.
Mouth Ulcers
- An In vitro study conducted to evaluate the antibacterial activity of Glycyrrhiza glabra against oral pathogens showed the extract successfully inhibit all of the 6 test bacterial strains. Thus, indicating the potential use of licorice in soothing mouth ulcers.
- This study demonstrates that the herbal extracts of Glycirrhiza Glabra, Jasminum Offcinale and Menta Piperita were successfully formulated into jelly formulations that are safe for consumption and showed good anti-inflammatory activity.
Obesity
- Ingredients in our product, Tab Obenyl, showed fair to excellent results in 84.33% patients in treating obesity (PDF format)
- Hypolipemic effect of AV UNILIPID on Human Volunteers
- “84.33% of obese patients showed a clinically significant response to a herb formulation in a clinical evaluation conducted for 6 weeks. The herbs were found effective in reducing obesity by checking excessive appetite and promoting diuresis.” 1*
Pelvic inflammatory disease
Polycystic Ovarian Syndrome (PCOS/PCOD)
Tinnitus
- 85% of Tinnitus patients reported a significant reduction in their condition after taking a herbal decoction for 30 days. None of the patients reported any side effects although 15% did not derive any benefits from the trial.
- Results of a double blind, randomized study to confirm the efficacy of Ginkgo in chronic tinnitus reported that Ginkgo (included in our kit) appeared to safely and effectively alleviate Tinnitus symptoms and the herb was well tolerated by the patients.
Trigeminal Neuralgia
- A group of physicians confirmed Trigeminal Neuralgia patients obtained an overall reduction of more than 60% in pain intensity and attack frequency using Natural Remedies. The results suggest that natural remedies may be an effective and safe method in the treatment of TN.
- A group of physicians reported that the combination of 4 Biogetica formulas improved the health rate of 68%TN patients.
Urticaria
- Studies of commonly prescribed medications for the treatment of urticaria showed that antihistamines provide only symptomatic relief. Also steroids and immunosuppressive drugs are best avoided because of their potentially harmful side effects.
- 88.796 % of allergic urticaria patients were benefited by the test herbal protocol in the clinical study conducted.
Vertigo
- 73% of recurrent vertigo patients on a herb trial for 2 to 45 days reported to have all their symptoms improved and had no relapse during the follow-up done for a year to seek long-term evidence.
- In a randomized, double blind controlled clinical study conducted on 119 vertigo patients in Germany and published in the Journal of the American Medical Association, Both the natural and conventional treatments showed a clinically relevant reduction in the duration, and intensity of the vertigo attacks. The therapeutic equivalence of the natural remedy and betahistine was established statistically. However the natural treatments group showed lesser frequency in attacks during treatment.