Kenya Medical
Research Institute's Charles Mbakaya, like
President Thabo Mbeki, writes Victor Bwire,
believes there is a nutrition angle to the
Aids pandemic and that is what is guiding
his research.
First there was Dr Davy Koech of the Kenya
Medical Research Institute (Kemri) and the
discovery of Kemron as an Aids drug in 1989.
It is no longer heard of. Then came Prof
Arthur Obel a decade later. Some say he
was designated Chief Government Scientist
and his Aids drug was called Pearl Omega.
Apart from flouting established scientific
research procedures in announcing the drug's
advent, Pearl Omega, too, is rarely heard
of these days. But now, there is a new kid
on the block with a different approach to
the search for an Aids management formula.
Charles Mbakaya He is not saying his is
the alpha and omega to the Aids pandemic,
but like South Africa's President Thabo
Mbeki, he says that Aids is not all about
sex. There is the nutrition angle to think
about.
It was when reading a copy of the British
Journal some 15 years ago, a Kenyan scientist,
Charles Mbakaya, made a note that still
torments him to this day.
The journal reported that HIV positive people
depicted symptoms similar to those in people
with a deficiency of zinc in their systems.
Even more important, was the journal's suggestion
that the mineral zinc was essential in the
biosynthesis of proteins, production of
thymulin and interferon's which have scientifically
proved to be very essential in the human
immunity system.
Two years ago, Mbakaya, who is a senior
science researcher at the Kenya Medical
Research Institute (Kemri), embarked on
the long journey for the search of a zinc
laden supplement that could help in reducing
the viral load in HIV positive people.
"As researcher I developed an interest in
the possible role nutrition could play in
health promotion, especially in immuno-compromised
persons," says Mbakaya.
"In any case, I have never believed that
Aids is singularly a function of sex. Why
is it more prevalent in nutrition deprived
areas and commonly symp- tomised by loss
of weight?" he asks. The Nairobi analytical
science graduate then picked on VIUSID -
due to its high zinc content - to investigate
its possible role in the management of HIV
patients in Kenya.
VIUSID is a nutritional preparation specially
designed to facilitate the increase of the
immunological deficiencies in all body processes
that cause immunodeficiency.
The antioxidant substances of VIUSID have the capacity to
eliminate the effects of the free radicals that appear in
all the infectious processes.
Through a new technology of molecular activation,
the chemical activities of the various ingredients
of VIUSID have greatly been enhanced without
changing its molecular structure.
It is manufactured by a Spanish company
- CATALYSIS Ltd and locally distributed
by Management Solutions.
It has been approved and is widely used
in 17 African countries. One is advised
to take 3 sachets a day for so long as he
gets better. A sachet goes for Sh100.
So two years ago, with consent from his
employers and assisted by Winfred Kisingu
from Kemri and Dr Patrick Orege from the
National Aids Control Council (NACC), Mbakaya
then started his long journey to the unknown.
Forty four persons from the Association
of People Living with Aids (TAPWAK), a national
organisation helping HIV positive individuals
to live a comfortable and positive life,
were chosen for the study.
"During the initial stages of the study,
we experienced a lot of problems. Ten people
dropped out of the study due to personal
problems while four later turned out to
be HIV negative on further tests," Mbakaya
says.
The soft spoken Mbakaya says more difficulties were to come
as three more died and professional sarcasm from colleagues
weighed in with morale as the main target.
Mbakaya says that during a seminar in Zimbabwe, he remembers
several scientists dismissing his study.
Many were of the view that the sample size was very small
and questioned the rationale of choosing that particular supplement
and not others.
In Lesotho during a meeting of scientific researchers, several
participants expressed dissatisfaction with Mbakaya's study.
He remembers one participant saying "That is not a study worthy
listening to. The guys spent all the time just observing an
uncontrolled objects than deal with a controlled sample."
But others have been very supportive of the study to the extent
that it has started shaping the HIV management agenda on the
African Continent.
"Many of the researchers we have shared the results with have
expressed their support. They believe that in resource stricken
countries, the benefits of our finding far outweigh the long
held views on the pandemic," says Mbakaya.
The results released after 24 months have shown that VIUSID
has the capacity to reduce the viral load in HIV positive
individuals by over 50 per cent and complete wipe it out sometimes.
Within 3 months of using the supplement, 80 per cent of the
patients reported that signs and symptoms associated with
HIV such as persistent headaches, night sweats, diarrhoea,
itchy skin, rashes and loss of appetite had resolved.
"Some patients even asked if they could be provided with food
to match their increased appetites," Mbakaya says.
Within one year of the study, more than 90 per cent of the
patients experienced a significant weight gain, with some
gaining as much as 10 kilogrammes.
Additionally, the HIV anti-bodies of the patients almost doubled
up within the 24 months of follow-up. This is an indication
that their acquired immunity against HIV had been stimulated.
Visible changes start being observed after 7 days of use and
in three months of uninterrupted use opportunistic infections
disappear.
In 52 per cent of the patients, their viral load reduced by
50 per cent within the study period, with 19 per cent attaining
undetectable viral load levels.
Clinically, the VIUSID has no marked side effects. All the
patients showed normal liver functions, an indication that
it had no toxic effects on the patients.
Mbakaya says that from that, it was clear that it could be
used for an extended period of time. "Our study then confirms
what other scientists have observed; that micro nutrient zinc
may be a critical factor in the transmission and progression
of Aids," Mbakaya emphatically concludes.
The researcher then advises that "nutrition has a critical
role in the management of HIV in resource deprived countries
such as Kenya."
Above all, VIUSID has the capacity to reduce the incidence
of opportunistic diseases related to HIV, resulting in improved
quality of life for the patients.
Additionally, the supplement improves appetite, increases
weight and increases patients immunity. Mbakaya, 39, vows
not to rest until home-grown solution for Aids are found.
He dismisses the current notion about the transmission of
the deadly disease, echoing South African's President Thabo
Mbeki that Africa should not wholly believe the Europeans'
views about HIV/Aids.
"There are other hidden cures for the disease other than the
drugs and vaccines being clamoured for," Mbakaya says.
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