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Clinical efficacy of "HERPIGEN" in management of the female herpes genitalis Doschanova A.M. - State National Medical University, Almaty

AIM: To assess efficacy of "HERPIGEN", an anti-viral preparation in management of females with herpes genitalis.

Materials and methods

22 females aged from 21 to 38 with clinical implications of herpetic viral infection comprised the group under observation. The infection presence was confirmed by the performed DNA PCR analysis. The patients' complaints and medical histories were studied with the examination of immunological status (A-, G- and M-class immunoglobulins). The PCR was employed in herpetic virus typing. We managed to assess the preparation efficacy, side effects and complications, presence or absence of ulcerous erosions and recurrence rate of herpetic viral infection.

Method of administration

The performed monotherapy comprised spraying of the skin surface and mucous membranes with "HERPIGEN" 6 times a day for 5-7 days. The females were followed-up 7-10 days after the therapy and further with onemonth interval for 6 months.

Patients' characteristics: 22 females with clinical implications of herpetic viral infection in exacerbation were examined and managed on the outpatient basis. All the females above had recurring herpes genitalis with various disease duration: the one of less than one year (n=14), from 1 to 5 years (n=6), 6-10 years (n=2). The disease recurrence rate was as follows: once a month (n=5), one time per two months (n=8), one times per three months (n=9). In 7 of 22 patients the rash was registered accompanied by hyperthermia (up to 37.5 degrees of Centigrade), fever, general indisposition and regional lymphadenitis.

Results: the findings of the performed clinical trial are indicative of high "HERPIGEN" efficacy in management of herpetic infections. 20 patients stopped complaining of itch and burning on the 2nd day of the therapy. The reduction of the complaints was observed in 2 females to terminate in all of the patients on the 3rd day of the therapy. First intention and herpetic erosion epithelization were detected to take place on the 2nd day and in the first 3 days of the therapy, respectively. The clinical effect absence was not registered in the management of herpetic affections. The increase in serum IgM was found. Reexamination a month after the therapy revealed no herpes simplex virus in 10 patients, 6 months after the therapy - in 5 more females. 6-month follow-up showed the recurrences in 5 persons. Neither allergic reactions nor side effects were registered.

Conclusion

"HERPIGEN" is a highly efficient, handy and tolerable preparation for external use in management of herpetic infection implications, causing no sides effects. The preparation can be recommended for wide use in medical practice. Slides

1. Advantages of administration in pregnancy:

The "HERPIGEN INTIM" spray - requires no special medical skills, being handy and easy in use without assistance;

produces rapid therapeutic effect; - being natural, produces no allergic and side reactions; - evokes no skin irritation, producing fine sanitizing effect; - is rapidly absorbed, being easily removed and leaving no stains on clothes; - has no embryotoxic and teratogenic effect with safety confidently experimentally and clinically confirmed.

2. Indication of use

Management of herpes viral infection caused by herpes simplex virus both in acute primary and in recurring course. · Herpes viral infection recurrence prevention. · Management of lichen shingles caused by Varicella -Zoster virus (in complex therapy). · Therapy of cytomegalovirus. · Management of papillomavirus infection caused by various types (oncogenic included), of human papilloma virus. · Therapy of non-specific colpitis and vaginosis, vaginal microflora normalization. · As prophylactic anti-viral and anti- inflammatory preparation in sexual intercourse

5. Glycyrrhizic acid is a kinase inhibitor.

It produces: · Anti-viral effect. · Anti-flammatory effect. · Anti-ulcerous effect · Anti-bacterial (bacteriostatic) effect · Interferogenic effect · Immunemodulating effect · Antipruritic effect · Produces rapid effect · Produces no side effect · Prolongs remission · Is absolute rapidly

6. HERPIGEN

Pharmacological peculiarities and mechanism of action. Glycyrrhizic acid is an essential active agent

Mechanism of action:

Glycyrrhizic acid inhibites DNA and RNA of :

Herpes simplex virus, Varicella -zoster, Hepatitis A virus, Influenza virus, Vesicular stomatitis virus, Human immunodeficiency virus
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There are however numerous clinical trials that address the effects of these products and we invite you to read these studies on our clinical trials page or on scholar.google.com. In fact we urge you to read any and all articles on our products so that you can make a sound judgment on whether these are products you desire to try. We support your right and freedom to choose natural remedies.

Does any allopathic, natural, ayurvedic, homeopathic, treatment cure herpes? This question is a matter of great controversy. Allopathic doctors often believe that there is no real cure, because viral antibodies tend to stay in the blood-stream for the patient's entire lifetime. For legal reasons, we do not claim to cure herpes, or have a genital herpes treatment. To read the background of natural remedies that have been traditionally used in ayurveda or homeopathy for addressing herpes please click here. To see the astounding results that hypericum mysoresnse or nosodes like 2lherp have had in clinical trials please click here. To read the full story on how to find the herpes cure found in the nilgiri hills please click here.

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"All homeopathic remedies are made in accordance with the Homeopathic Pharmacopeia of the United States, a document which has been published for over 100 years and which is recognized as an "official compendium" by Sections 501(b) and 502(e)(3) of the Federal Food, Drug, and Cosmetic Act, 21 U.S.C. 351(b) and 352(e)(3) ("FD&C Act")."

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Results may not be typical. We do not support third party claims and do not make any medical claims on our products. Please research the ingredients and choose for yourself or with your Dr's.

*These supplementary natural products are meant to complement conventional treatments.* They should not be considered as a replacement for medical advice and treatment. They are not meant to diagnose, mitigate, prevent, cure or treat any disease.

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*Keep out of reach of children. Do not exceed recommended dose. Do not use if outer or inner seal is broken or damaged. If you have a serious adverse reaction to product, discontinue use immediately, seek medical attention if necessary, and contact us. If you are undergoing treatment for a medical condition or if you are pregnant or lactating, consult your physician when taking this product.

*** These were lab tests only. We are not making any medical claims about the efficacy of Hypericum Mysorense in treating or curing herpes in human-beings. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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